This is a list of characters who were antagonists in the Lethal Weapon Series.
Bold stands for major antagonists.
- Mr. Joshua: McAllister's right hand man in the group and Shadow Company's negotiator.
- Gustaf: Shadow Company's secondary negotiator and a mercenary.
Arjen Rudd: The head of diplomatic communications and consul of South Africa.
- Pieter Vorstedt: Rudd's primary hitman and the murderer of Martin Riggs' wife Victoria.
- Hans: The henchman responsible for exposing the krugerrands by mistake to the police.
- Tyrone: A Gangster and Travis' number one buyer who deals the ammunition to his gang.
- Hatchett: Loyal henchman to Jack Travis and prepares the firearms ready to be shipped to the black market.
- Billy Phelps: One of the robbery suspects who gets captured by Martin Riggs and Roger Murtaugh.
- Smitty: One of the robbery suspects who escapes from the cops.
- Darryl Smithers: A friend to Nick Murtaugh working for Travis.
- Hubie Bartholomew Smith: A henchman to Travis.
- Hershel: A minor henchman to Travis.
Wah Sing Ku: Highest rank Triad negotiator trying to get his brother and the Four Fathers out of prison.
- Uncle Benny Chan: Crime boss for the Triads, in charge of smuggling illegal immigrants from China into the United States.
- Chinese General: An official who runs a prison in China, where he's holding the Four Fathers captive.
- Chinese Captain : A chinese captain.